036446-PE
Clone Type
PolyclonalHost
RabbitSource
HumanConjugate
PEIsotype
IgGGrade
Affinity PurifiedApplications
FLISA WBCrossreactivity
HuAccession #
NP_005321.1; P02100Gene ID
3046Gene #
HBE1Shipping Temp
Blue IceStorage Temp
4°C Do Not FreezeNotes
Preservative Free
Rabbit Anti-HBE1v (HBE1, HBE, Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain) (PE)
HBE1, HBE, Hemoglobin subunit epsilon, Epsilon-globin, Hemoglobin epsilon chain
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3'
Applications
Suitable for use in Western Blot, FLISA
Recommended Dilution
FLISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 55-83 in the central region of human HBE1v, UniProt Accession #NP_005321.1; P02100.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human HBE1v.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Nuinoon, M., et al. Hum. Genet. (2009) In press 2. Tachavanich, K., et al. Southeast Asian J. Trop. Med. Public Health 40(2):306-316(2009) 3. Naka, I., et al. Biochem. Genet. 46 (11-12), 708-711 (2008) 4. Winichagoon, P., et al. Transl Res 152(4):178-184(2008) 5. Das, B., et al. Ann. Hum. Biol. 35(4):422-431(2008)USBio References
No references available