Technical Data

036452
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_005323.1
Gene ID
3050
Gene #
HBZ
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-HBZ, CT (HBZ, HBZ2, Hemoglobin subunit zeta, HBAZ, Hemoglobin zeta chain, Zeta-globin)
HBZ, HBZ2, Hemoglobin subunit zeta, HBAZ, Hemoglobin zeta chain, Zeta-globin

Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
HBZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the C-terminal region of human HBZ.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Hivin, P., et al. J. Cell. Sci. 118 (PT 7), 1355-1362 (2005) :|He, Z., et al. Biochem. Biophys. Res. Commun. 325(4):1376-1382(2004)|Kidd, R.D., et al. Biochemistry 40(51):15669-15675(2001)|Lau, E.T., et al. Prenat. Diagn. 21(7):529-539(2001)|Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001)
USBio References
No references available
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