Technical Data

036454
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Gene ID
3052
Gene #
HCCS
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-HCCS, ID (HCCS, CCHL, Cytochrome c-type heme lyase, Holocytochrome c-type synthase)
HCCS, CCHL, Cytochrome c-type heme lyase, Holocytochrome c-type synthase

The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.

Applications
Suitable for use in Western Blot, Immunohistochemistry
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
HCCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179~209 amino acids from the Central region of human HCCS.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)|Wimplinger, I., et al. Mol. Vis. 13, 1475-1482 (2007) |Wimplinger, I., et al. Am. J. Hum. Genet. 79(5):878-889(2006)|Nakashima-Kamimura, N., et al. J. Cell. Sci. 118 (PT 22), 5357-5367 (2005) |Prakash, S.K., et al. Hum. Mol. Genet. 11(25):3237-3248(2002)
USBio References
No references available
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