Technical Data

036471
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001516.2; O43613
Gene ID
3061
Gene #
HCRTR1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-Orexin Receptor 1, ID
(OX1R, HCRTR1, Hcrt Receptor 1, Hypocretin Receptor 1, Hypocretin Type 1 Receptor, Hypocretin Receptor-1, Orexin Receptor Type 1, Orexin Type 1 Receptor, Orexin-1 Receptor, OX1 Receptor, Orexin a Receptor, Orexin Receptor-1, OX-R1, Ox1-R, Hypocretin (orexin) Receptor 1, Hypocretin Receptor Type 1, Ox-1-R

The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
HCRTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the Central region of human HCRTR1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Peltonen, H.M., et al. Biochim. Biophys. Acta 1803(10):1206-1212(2010)|Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)|Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :|Turunen, P.M., et al. Br. J. Pharmacol. 159(1):212-221(2010)|El Firar, A., et al. FASEB J. 23(12):4069-4080(2009)
USBio References
No references available
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