Technical Data

036628
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_002117.1
Gene ID
3131
Gene #
HLF
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-HLF, CT (HLF, Hepatic leukemia factor)
HLF, Hepatic leukemia factor

This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
HLF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-232 amino acids from the C-terminal region of human HLF.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Hirose, K., et al. Blood 116(6):962-970(2010)|Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)|Otto, T., et al. Endocrinology 149(5):2241-2250(2008)|Inukai, T., et al. Leukemia 21(2):288-296(2007)|He, J., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 22(5):551-553(2005)
USBio References
No references available
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