Technical Data

036645
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_005508.1
Gene ID
3151
Gene #
HMGN2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-HMGN2, NT (HMGN2, HMG17, Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2)
HMGN2, HMG17, Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2

HMGN2 binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation (By similarity).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
HMGN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Rattner, B.P., et al. Mol. Cell 34(5):620-626(2009)|Ueda, T., et al. Mol. Cell. Biol. 28(9):2872-2883(2008)|Cherukuri, S., et al. Mol. Biol. Cell 19(5):1816-1824(2008)|Wu, C., et al. Proteomics 7(11):1775-1785(2007)|Porkka, K., et al. Proc. Natl. Acad. Sci. U.S.A. 99(11):7444-7449(2002)
USBio References
No references available
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