Technical Data

036669
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_112556
Gene ID
3182
Gene #
HNRNPAB
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-HNRPAB, NT (HNRNPAB, ABBP1, HNRPAB, Heterogeneous nuclear ribonucleoprotein A/B, APOBEC1-binding protein 1)
HNRNPAB, ABBP1, HNRPAB, Heterogeneous nuclear ribonucleoprotein A/B, APOBEC1-binding protein 1

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
HNRPAB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-38 amino acids from the N-terminal region of human HNRPAB.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Jonson, L., et al. Mol. Cell Proteomics 6(5):798-811(2007)|Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :|Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)|Ong, S.E., et al. Nat. Methods 1(2):119-126(2004)
USBio References
No references available
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