Technical Data

036992
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
NP_003845.2
Gene ID
8808
Gene #
IL1RL2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-IL1RL2, ID (IL1RL2, IL1RRP2, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2)
IL1RL2, IL1RRP2, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2

The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

Applications
Suitable for use in ELISA, Western Blot and Indirect Flow Cytometry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:8000 Flow Cytometry (Indirect): 1:25 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 257-286 in the central region of human IL1RL2. Cellular Localization: Membrane; single-pass type 1 membrane protein.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human IL1RL2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Davila, S., et al. Genes Immun. 11(3):232-238(2010). 2. Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010). 3. Nakki, A., et al. BMC Med. Genet. 11 (1), 50 (2010). 4. Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009). 5. Solovieva, S., et al. J. Rheumatol. 36(9):1977-1986(2009)
USBio References
No references available
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