Technical Data

037005
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_742151.2
Gene ID
282617
Gene #
IL28B
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-IL28B, NT (IL28B, IFNL3, IFNL4, IL28C, ZCYTO22, Interleukin-28B, Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, Interleukin-28C)
IL28B, IFNL3, IFNL4, IL28C, ZCYTO22, Interleukin-28B, Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, Interleukin-28C

This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
IL28B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-63 amino acids from the N-terminal region of human IL28B.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Lindh, M., et al. Hepatology 52(5):1860-1861(2010)|Pineda, J.A., et al. Clin. Infect. Dis. 51(7):788-795(2010)|Grebely, J., et al. Hepatology 52(4):1216-1224(2010)|Stattermayer, A.F., et al. Clin. Gastroenterol. Hepatol. (2010) In press :|Iwata, R., et al. J. Viral Hepat. (2010) In press :
USBio References
No references available
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