Technical Data

037089
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_003861.1
Gene ID
8826
Gene #
IQGAP1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-IQGAP1, NT (IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195)
IQGAP1, KIAA0051, Ras GTPase-activating-like protein IQGAP1, p195

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
IQGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-285 amino acids from the N-terminal region of human IQGAP1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Hayashi, H., et al. Int. J. Cancer 126(11):2563-2574(2010)|Liang, S., et al. Proteomics 10(7):1474-1483(2010)|Nakhaei-Nejad, M., et al. Eur. J. Immunol. 40(1):204-213(2010)|Wang, J.B., et al. J. Cell. Sci. 122 (PT 12), 2024-2033 (2009) :|Usatyuk, P.V., et al. J. Biol. Chem. 284(22):15339-15352(2009)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net