Technical Data

037119
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_002192.2
Gene ID
3669
Gene #
ISG20
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ISG20, ID (ISG20, HEM45, Interferon-stimulated gene 20kD protein, Estrogen-regulated transcript 45 protein, Promyelocytic leukemia nuclear body-associated protein ISG20)
ISG20, HEM45, Interferon-stimulated gene 20kD protein, Estrogen-regulated transcript 45 protein, Promyelocytic leukemia nuclear body-associated protein ISG20

Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ISG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-58 amino acids from the Central region of human ISG20.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Hao, Y., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 28(1):11-13(2008)|Horio, T., et al. FEBS Lett. 577 (1-2), 111-116 (2004) :|Espert, L., et al. J. Biol. Chem. 278(18):16151-16158(2003)|Izmailova, E., et al. Nat. Med. 9(2):191-197(2003)|Nguyen, L.H., et al. Biochemistry 40(24):7174-7179(2001)
USBio References
No references available
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