Technical Data

037327
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001181887.1; B7U540
Gene ID
100134444
Gene #
KCNJ18
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-KCNJ18, NT (KCNJ18, Inward rectifier potassium channel 18, Inward rectifier K(+) channel Kir2.6, Potassium channel, inwardly rectifying subfamily J member 18)
KCNJ18, Inward rectifier potassium channel 18, Inward rectifier K(+) channel Kir2.6, Potassium channel, inwardly rectifying subfamily J member 18

Inwardly rectifying potassium channels, such as KCNJ18, maintain resting membrane potential in excitable cells and aid in repolarization of cells following depolarization. KCNJ18 is primarily expressed in skeletal muscle and is transcriptionally regulated by thyroid hormone (Ryan et al., 2010 [PubMed 20074522]).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KCNJ18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human KCNJ18.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Ryan, D.P., et al. Cell 140(1):88-98(2010)
USBio References
No references available
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