Technical Data

037342
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_852006.1
Gene ID
10242
Gene #
KCNMB2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-KCNMB2, NT (KCNMB2, Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K(VCA)beta-2, Maxi K channel subunit beta-2, Slo-beta-2)
KCNMB2, Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, Hbeta3, K(VCA)beta-2, Maxi K channel subunit beta-2, Slo-beta-2

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene. [provided by RefSeq].

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KCNMB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 0-28 amino acids from the N-terminal region of human KCNMB2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Trevino, L.R., et al. Nat. Genet. 41(9):1001-1005(2009)|Lee, U.S., et al. J. Physiol. (Lond.) 587 (PT 7), 1481-1498 (2009) :|Zarei, M.M., et al. Neuroscience 147(1):80-89(2007)|Zeng, X.H., et al. J. Neurosci. 27(17):4707-4715(2007)|Orio, P., et al. J. Gen. Physiol. 127(2):191-204(2006)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net