Technical Data

037523
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu Mo
Accession #
NP_619638.1
Gene ID
136259
Gene #
KLF14
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-KLF14, CT (KLF14, BTEB5, Krueppel-like factor 14, Basic transcription element-binding protein 5, Transcription factor BTEB5)
KLF14, BTEB5, Krueppel-like factor 14, Basic transcription element-binding protein 5, Transcription factor BTEB5

This gene encodes a member of the Kruppel-like family of transcription factors. The gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. Expression of this gene is induced by TGF-beta, and the protein represses TGF-beta receptor II expression. The protein functions as part of a transcriptional co-repressor complex that also contains the transcriptional regulator SIN3A and histone deacetylase 2.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-291 amino acids from the C-terminal region of human KLF14.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Voight, B.F., et al. Nat. Genet. 42(7):579-589(2010) Chasman, D.I., et al. PLoS Genet. 5 (11), E1000730 (2009) : Stacey, S.N., et al. Nat. Genet. 41(8):909-914(2009) Truty, M.J., et al. J. Biol. Chem. 284(10):6291-6300(2009) Parker-Katiraee, L., et al. PLoS Genet. 3 (5), E65 (2007) :
USBio References
No references available
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