Technical Data

037780
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_085915.2; NP_001155220.1
Gene ID
3982
Gene #
LIM2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-LIM2, CT (LIM2, Lens fiber membrane intrinsic protein, MP18, MP19, MP20)
LIM2, Lens fiber membrane intrinsic protein, MP18, MP19, MP20

LIM2 is an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
LIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the C-terminal region of human LIM2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Ponnam, S.P., et al. Mol. Vis. 14, 1204-1208 (2008) :|Hsu, H., et al. Sheng Wu Gong Cheng Xue Bao 20(4):507-515(2004)|Wistow, G., et al. Mol. Vis. 8, 171-184 (2002) :|Wistow, G., et al. Mol. Vis. 8, 185-195 (2002) :|Pras, E., et al. Am. J. Hum. Genet. 70(5):1363-1367(2002)
USBio References
No references available
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