Technical Data

037901
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_004784.2
Gene ID
9361
Gene #
LONP1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-LONP1, ID (LONP1, PRSS15, Lon protease homolog, mitochondrial, LONHs, Lon protease-like protein, Mitochondrial ATP-dependent protease Lon, Serine protease 15)
LONP1, PRSS15, Lon protease homolog, mitochondrial, LONHs, Lon protease-like protein, Mitochondrial ATP-dependent protease Lon, Serine protease 15

This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Hansen, J., et al. Neuroscience 153(2):474-482(2008)|Chen, S.H., et al. Nucleic Acids Res. 36(4):1273-1287(2008)|Bogenhagen, D.F., et al. J. Biol. Chem. 283(6):3665-3675(2008)|Bayot, A., et al. Biochimie 90(2):260-269(2008)|Xue, X., et al. Nan Fang Yi Ke Da Xue Xue Bao 27(6):870-874(2007)
USBio References
No references available
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