Technical Data

037911
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_056051.2
Gene ID
23284
Gene #
LPHN3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-LPHN3, NT (LPHN3, KIAA0768, LEC3, Latrophilin-3, Calcium-independent alpha-latrotoxin receptor 3, Lectomedin-3)
LPHN3, KIAA0768, LEC3, Latrophilin-3, Calcium-independent alpha-latrotoxin receptor 3, Lectomedin-3

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
LPHN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-397 amino acids from the N-terminal region of human LPHN3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Arcos-Burgos, M., et al. Mol. Psychiatry 15(11):1053-1066(2010)|Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)|Kasperaviciute, D., et al. Brain 133 (PT 7), 2136-2147 (2010) :|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009)
USBio References
No references available
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