Technical Data

038054
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_055443.1; NP_001003690.1
Gene ID
9587
Gene #
MAD2L1BP
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MAD2L1BP, NT (MAD2L1BP, CMT2, KIAA0110, MAD2L1-binding protein, Caught by MAD2 protein)
MAD2L1BP, CMT2, KIAA0110, MAD2L1-binding protein, Caught by MAD2 protein

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MAD2L1BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAD2L1BP.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Yun, M., et al. Mol. Cancer Res. 7(3):371-382(2009)|Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)|Yang, M., et al. Cell 131(4):744-755(2007)|Yun, M.Y., et al. Exp. Mol. Med. 39(4):508-513(2007)|Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net