Technical Data

038061
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
NP_005452.2
Gene ID
9935
Gene #
MAFB
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MAFB, CT (MAFB, KRML, Transcription factor MafB, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B)
MAFB, KRML, Transcription factor MafB, V-maf musculoaponeurotic fibrosarcoma oncogene homolog B

The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that plays an important role in the regulation of lineage-specific hematopoiesis. The encoded nuclear protein represses ETS1-mediated transcription of erythroid-specific genes in myeloid cells. This gene contains no introns. [provided by RefSeq].

Applications
Suitable for use in ELISA, Western Blot and Indirect Flow Cytometry. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 266-292 in the C-terminal region of human MAFB. Species Sequence Homology: monkey, mouse, rat, Xenopus
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human MAFB.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Kim, H., et al. Nat. Immunol. 11(8):743-750(2010) 2. Beaty, T.H., et al. Nat. Genet. 42(6):525-529(2010) 3. Vatsveen, T.K., et al. Leuk. Res. 33(12):1670-1677(2009) 4. Zanocco-Marani, T., et al. Exp. Cell Res. 315(11):1798-1808(2009) 5. Kathiresan, S., et al. Nat. Genet. 41(1):56-65(2009)
USBio References
1. Hasan S., et al. Myelo-erythroid commitment after burn injury is under β-adrenergic control via MafB regulation. 2017. Am J Physiol. 312(3):C286-C301.
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