Technical Data

038413
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
NP_002401.1
Gene ID
4249
Gene #
MGAT5
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MGAT5, CT (MGAT5, GGNT5, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, GlcNAc-T V, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V)
MGAT5, GGNT5, Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A, Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase, GlcNAc-T V, Mannoside acetylglucosaminyltransferase 5, N-acetylglucosaminyl-transferase V

This gene encodes mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, a glycosyltransferase involved in the synthesis of protein-bound and lipid-bound oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the encoded protein's activity may correlate with the progression of invasive malignancies.

Applications
Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Flow Cytometry (Indirect): 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 652-680 in the C-terminal region of human MGAT5
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human MGAT5

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Dick, D.M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (6), 1179-1188 (2010). 2. Brynedal, B., et al. J. Neuroimmunol. 220 (1-2), 120-124 (2010) 3. Benson, V., et al. Int. Immunol. 22(3):167-177 (2010). 4. Wang, C., et al. J. Cell. Biochem. 109(1):113-123 (2010). 5. Ding, H., et al. Stroke 41(1):177-180 (2010)
USBio References
No references available
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