Technical Data

038461
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_055981.1
Gene ID
23209
Gene #
MLC1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MLC1, CT (MLC1, KIAA0027, WKL1, Membrane protein MLC1)
MLC1, KIAA0027, WKL1, Membrane protein MLC1

The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MLC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the C-terminal region of human MLC1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Yis, U., et al. Turk. J. Pediatr. 52(2):179-183(2010)|Lanciotti, A., et al. Neurobiol. Dis. 37(3):581-595(2010)|Shukla, P., et al. Prenat. Diagn. 28(4):357-359(2008)|Ambrosini, E., et al. Mol. Cell. Neurosci. 37(3):480-493(2008)|Selch, S., et al. Biol. Psychiatry 61(10):1211-1214(2007)
USBio References
No references available
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