038506
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_002420.1Gene ID
4327Gene #
MMP19Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-MMP19, NT (MMP19, MMP18, RASI, Matrix metalloproteinase-19, Matrix metalloproteinase RASI, Matrix metalloproteinase-18)
MMP19, MMP18, RASI, Matrix metalloproteinase-19, Matrix metalloproteinase RASI, Matrix metalloproteinase-18
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This protein is expressed in human epidermis and it has a role in cellular proliferation as well as migration and adhesion to type I collagen. Multiple transcript variants encoding distict isoforms have been identified for this gene.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MMP19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-84 amino acids from the N-terminal region of human MMP19.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :|Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :|Muller, M., et al. Mod. Pathol. 23(4):511-521(2010)|Lettau, I., et al. J. Neuropathol. Exp. Neurol. 69(3):215-223(2010)USBio References
No references available