Technical Data

038530
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_004522.1; O96007
Gene ID
4338
Gene #
MOCS2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MOCS2, NT (MOCS2, MCBPE, MOCO1, Molybdopterin synthase catalytic subunit, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, Molybdopterin-synthase large subunit)
MOCS2, MCBPE, MOCO1, Molybdopterin synthase catalytic subunit, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, Molybdopterin-synthase large subunit

Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MOCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-43 amino acids from the N-terminal region of human MOCS2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Per, H., et al. Brain Dev. 29(6):365-368(2007)|Hahnewald, R., et al. Mol. Genet. Metab. 89(3):210-213(2006)|Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)|Leimkuhler, S., et al. Hum. Genet. 117(6):565-570(2005)|Matthies, A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(16):5946-5951(2004)
USBio References
No references available
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