038550-Biotin
Clone Type
PolyclonalHost
RabbitConjugate
BiotinIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
MoAccession #
NP_060368.2 (human)Gene ID
54996Gene #
MOSC2Shipping Temp
Blue IceStorage Temp
-20°CNotes
Preservative Free
Rabbit Anti-MOSC2, CT (MARC2, MOSC2, MOSC domain-containing protein 2, mitochondrial, Mitochondrial amidoxime reducing component 2, Moco sulfurase C-terminal domain-containing protein 2, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (Biotin)
MARC2, MOSC2, MOSC domain-containing protein 2, mitochondrial, Mitochondrial amidoxime reducing component 2, Moco sulfurase C-terminal domain-containing protein 2, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2
Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.
Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 304-333 in the C-terminal region of human MOSC2. Species Sequence Homology: monkey and rat
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes MOSC2. Species Crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010). 2. Aberg, K., et al. Biol. Psychiatry 67(3):279-282(2010). 3. Havemeyer, A., et al. J. Biol. Chem. 281(46):34796-34802(2006). 4. Anantharaman, V., et al. FEMS Microbiol. Lett. 207(1):55-61(2002). 5. Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)USBio References
No references available