Technical Data

038556
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
O75352;NP_004861.2
Gene ID
9526
Gene #
MPDU1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MPDU1, CT (MPDU1, Mannose-P-dolichol utilization defect 1 protein, Suppressor of Lec15 and Lec35 glycosylation mutation homolog)
MPDU1, Mannose-P-dolichol utilization defect 1 protein, Suppressor of Lec15 and Lec35 glycosylation mutation homolog

This gene encodes an endoplasmic reticulum membrane protein that is required for utilization of the mannose donor mannose-P-dolichol in the synthesis of lipid-linked oligosaccharides and glycosylphosphatidylinositols. Mutations in this gene result in congenital disorder of glycosylation type If. Alternative splicing results in multiple transcript variants.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MPDU1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the C-terminal region of human MPDU1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)|Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)|Shen, M., et al. Environ. Mol. Mutagen. 50(4):285-290(2009)|Hosgood, H.D. III, et al. Carcinogenesis 29(10):1938-1943(2008)|Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
USBio References
No references available
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