038693-PE
Clone Type
PolyclonalHost
RabbitSource
HumanConjugate
PEIsotype
IgGGrade
Affinity PurifiedApplications
FLISA IF IHC WBCrossreactivity
HuGene ID
200958Gene #
MUC20Shipping Temp
Blue IceStorage Temp
4°C Do Not FreezeNotes
Preservative Free
Rabbit Anti-MUC20, CT (MUC20, KIAA1359, Mucin-20) (PE)
MUC20, KIAA1359, Mucin-20
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry (Not Tested) and FLISA. Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry (Leica): Formalin-fixed, paraffin-embedded sections. Requires HIER using EDTA pH 9.0 Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 654-684 in the C-terminal region of human MUC20.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human MUC20.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Li,G., Am. J. Nephrol. 26 (1), 43-49 (2006) 2. Suzuki,Y., Genome Res. 14 (9), 1711-1718 (2004) 3. Higuchi,T., Mol. Cell. Biol. 24 (17), 7456-7468 (2004) 4. Higuchi,T., J. Biol. Chem. 279 (3), 1968-1979 (2004)USBio References
No references available