Technical Data

038698
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_116242.2
Gene ID
84939
Gene #
MUM1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MUM1, CT (MUM1, EXPAND1, PWWP domain-containing protein MUM1, Mutated melanoma-associated antigen 1, Protein expandere)
MUM1, EXPAND1, PWWP domain-containing protein MUM1, Mutated melanoma-associated antigen 1, Protein expandere

Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MUM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 670-699 amino acids from the C-terminal region of human MUM1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Huen, M.S., et al. Mol. Cell 37(6):854-864(2010)|Matsuoka, S., et al. Science 316(5828):1160-1166(2007)|Coulie, P.G., et al. Proc. Natl. Acad. Sci. U.S.A. 92(17):7976-7980(1995)
USBio References
No references available
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