Technical Data

038714
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_002456.2; NP_996555.1
Gene ID
4604
Gene #
MYBPC1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-MYBPC1, ID (MYBPC1, MYBPCS, Myosin-binding protein C, slow-type, C-protein, skeletal muscle slow isoform)
MYBPC1, MYBPCS, Myosin-binding protein C, slow-type, C-protein, skeletal muscle slow isoform

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
MYBPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 749-778 amino acids from the Central region of human MYBPC1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Gurnett, C.A., et al. Hum. Mol. Genet. 19(7):1165-1173(2010)|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Flashman, E., et al. Biochem. J. 401(1):97-102(2007)
USBio References
No references available
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