Technical Data

038848
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001123959.1; NP_065198.1
Gene ID
65009
Gene #
NDRG4
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-NDRG4, ID (NDRG4, BDM1, KIAA1180, Protein NDRG4, Brain development-related molecule 1, N-myc downstream-regulated gene 4 protein, Vascular smooth muscle cell-associated protein 8)
NDRG4, BDM1, KIAA1180, Protein NDRG4, Brain development-related molecule 1, N-myc downstream-regulated gene 4 protein, Vascular smooth muscle cell-associated protein 8

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].

Applications
Suitablle for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 193-220 from the Central region of human NDRG4. Species sequence homology: mouse, rat.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human NDRG4.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Rose, J. Phd, et al. Mol. Med. (2010) In press, 2. Holm, H., et al. Nat. Genet. 42(2):117-122(2010), 3. Schilling, S.H., et al. J. Biol. Chem. 284(37):25160-25169(2009), 4. Melotte, V., et al. J. Natl. Cancer Inst. 101(13):916-927(2009), 5. Pfeufer, A., et al. Nat. Genet. 41(4):407-414(2009)
USBio References
No references available
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