Technical Data

038961
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_005589.1
Gene ID
4807
Gene #
NHLH1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-NHLH1, ID (NHLH1, BHLHA35, HEN1, Helix-loop-helix protein 1, Class A basic helix-loop-helix protein 35, Nescient helix loop helix 1)
NHLH1, BHLHA35, HEN1, Helix-loop-helix protein 1, Class A basic helix-loop-helix protein 35, Nescient helix loop helix 1

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM].

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
NHLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-67 amino acids from the Central region of human NHLH1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Manetopoulos, C., et al. Biochem. Biophys. Res. Commun. 307(4):891-899(2003)|Bao, J., et al. Development 127(2):425-435(2000)|Lipkowitz, S., et al. J. Biol. Chem. 267(29):21065-21071(1992)|Brown, L., et al. Proc. Natl. Acad. Sci. U.S.A. 89(18):8492-8496(1992)|Begley, C.G., et al. Proc. Natl. Acad. Sci. U.S.A. 89(1):38-42(1992)
USBio References
No references available
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