Technical Data

039244
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
O95190; NP_002528.1
Gene ID
4947
Gene #
OAZ2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-OAZ2, CT (OAZ2, Ornithine decarboxylase antizyme 2)
OAZ2, Ornithine decarboxylase antizyme 2

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. [provided by RefSeq].

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
OAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the C-terminal region of human OAZ2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Geerts, D., et al. Int. J. Cancer 126(9):2012-2024(2010)|Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :|Mangold, U., et al. Biochem. J. 385 (PT 1), 21-28 (2005) :|Chen, H., et al. J. Biol. Chem. 277(48):45957-45961(2002)|Coffino, P. Proc. Natl. Acad. Sci. U.S.A. 97(9):4421-4423(2000)
USBio References
No references available
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