Technical Data

039468
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
FC WB
Crossreactivity
Hu
Accession #
NP_001005494.1
Gene ID
341418
Gene #
OR6C4
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-OR6C4, CT (OR6C4, Olfactory receptor 6C4, Olfactory receptor OR12-10)
OR6C4, Olfactory receptor 6C4, Olfactory receptor OR12-10

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Applications
Suitable for use in Western Blot and Indirect Flow Cytometry. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to a portion of amino acids within aa242-270 from the C-terminal region of human OR6C4 (NP_001005494), conjugated to KLH.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human OR6C4.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004) Youngblood, K., et al. J. Clin. Invest. 93(2):852-861(1994) Lauzurica, P., et al. J. Immunol. 148(11):3624-3630(1992)
USBio References
No references available
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