Technical Data

039582
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_002554.1
Gene ID
5028
Gene #
P2RY1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-P2RY1, ID (P2RY1, P2Y purinoceptor 1, ATP receptor, Purinergic receptor)
P2RY1, P2Y purinoceptor 1, ATP receptor, Purinergic receptor

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq].

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
P2RY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the Central region of human P2RY1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Maloney, S.F., et al. Integr Biol (Camb) 2(4):183-192(2010)|Nisar, S., et al. Traffic 11(4):508-519(2010)|Kumar, T.S., et al. J. Med. Chem. 53(6):2562-2576(2010)|Bambace, N.M., et al. Platelets 21(2):85-93(2010)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net