Technical Data

039654
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_003622.2
Gene ID
8505
Gene #
PARG
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PARG, CT (PARG, Poly(ADP-ribose) glycohydrolase)
PARG, Poly(ADP-ribose) glycohydrolase

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PARG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 820-849 amino acids from the C-terminal region of human PARG.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Whatcott, C.J., et al. Exp. Cell Res. 315(20):3477-3485(2009)|Frizzell, K.M., et al. J. Biol. Chem. 284(49):33926-33938(2009)|Erdelyi, K., et al. FASEB J. 23(10):3553-3563(2009)|Ame, J.C., et al. J. Cell. Sci. 122 (PT 12), 1990-2002 (2009) :|Uchiumi, F., et al. Genes Cells 13(12):1229-1247(2008)
USBio References
No references available
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