PCOLCE2 binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 201-230 in the central region of human PCOLCE2, UniProt Accession #NP_037495.1; Q9UKZ9 .
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes human PCOLCE2. Species Crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Zhu, J., et al. J. Lipid Res. 50(7):1330-1339(2009). 2. Steiglitz, B.M., et al. J. Biol. Chem. 277(51):49820-49830(2002). 3. Steiglitz, B.M., et al. Cytogenet. Cell Genet. 95 (3-4), 244-245 (2001). 4. Xu, H., et al. Genomics 66(3):264-273(2000)
USBio References
No references available
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