Technical Data

039871
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_065702.2
Gene ID
57162
Gene #
PELI1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PELI1, ID (PELI1, PRISM, E3 ubiquitin-protein ligase pellino homolog 1, Pellino-related intracellular-signaling molecule)
PELI1, PRISM, E3 ubiquitin-protein ligase pellino homolog 1, Pellino-related intracellular-signaling molecule

Scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PELI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 176-204 amino acids selected from the Central region of human PELI1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Ordureau, A., et al. Biochem. J. 409(1):43-52(2008)|Butler, M.P., et al. J. Biol. Chem. 282(41):29729-29737(2007)|Lamesch, P., et al. Genomics 89(3):307-315(2007)|Choi, K.C., et al. Nat. Immunol. 7(10):1057-1065(2006)|Butler, M.P., et al. J. Biol. Chem. 280(30):27759-27768(2005)
USBio References
No references available
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