039882
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_002607.2; O15534Gene ID
5187Gene #
PER1Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-PER1, CT (PER1, KIAA0482, PER, RIGUI, Period circadian protein homolog 1, Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui)
PER1, KIAA0482, PER, RIGUI, Period circadian protein homolog 1, Circadian clock protein PERIOD 1, Circadian pacemaker protein Rigui
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PER1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1155-1183 amino acids from the C-terminal region of human PER1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Xia, H.C., et al. Can J Neurol Sci 37(3):365-370(2010)|Soria, V., et al. Neuropsychopharmacology 35(6):1279-1289(2010)|Utge, S.J., et al. PLoS ONE 5 (2), E9259 (2010) :|Zhu, Y., et al. Cancer Res. 69(24):9315-9322(2009)|Pendergast, J.S., et al. J. Neurosci. 29(46):14681-14686(2009)USBio References
No references available