Technical Data

039914
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_219487.3
Gene ID
93210
Gene #
PGAP3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PGAP3, ID (PGAP3, CAB2, PERLD1, Post-GPI attachment to proteins factor 3, COS16 homolog, Gene coamplified with ERBB2 protein, PER1-like domain-containing protein 1)
PGAP3, CAB2, PERLD1, Post-GPI attachment to proteins factor 3, COS16 homolog, Gene coamplified with ERBB2 protein, PER1-like domain-containing protein 1

PGAP3 is involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins. Required for phospholipase A2 activity that removes an acyl-chain at the sn-2 position of GPI-anchors during the remodeling of GPI (Probable).

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PGAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-169 amino acids from the Central region of human PGAP3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care (2010) In press :|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)|Maeda, Y., et al. Mol. Biol. Cell 18(4):1497-1506(2007)|Benusiglio, P.R., et al. Br. J. Cancer 95(12):1689-1695(2006)
USBio References
No references available
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Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net