Technical Data

039945
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Mo
Accession #
NP_079176.2
Gene ID
79960
Gene #
PHF17
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PHF17, NT (PHF17, JADE1, KIAA1807, Protein Jade-1, PHD finger protein 17)
PHF17, JADE1, KIAA1807, Protein Jade-1, PHD finger protein 17

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PHF17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-51 amino acids from the N-terminal region of human PHF17.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Foy, R.L., et al. J. Biol. Chem. 283(43):28817-28826(2008)|Chitalia, V.C., et al. Nat. Cell Biol. 10(10):1208-1216(2008)|Olsen, J.V., et al. Cell 127(3):635-648(2006)|Lim, J., et al. Cell 125(4):801-814(2006)|Doyon, Y., et al. Mol. Cell 21(1):51-64(2006)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net