Technical Data

040080
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_055275.1
Gene ID
27254
Gene #
CSDC2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PIPPIN, ID (CSDC2, PIPPIN, Cold shock domain-containing protein C2, RNA-binding protein PIPPin)
CSDC2, PIPPIN, Cold shock domain-containing protein C2, RNA-binding protein PIPPin

RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PIPPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-105 amino acids from the Central region of human PIPPIN.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Wu, C., et al. Proteomics 7(11):1775-1785(2007)|Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :|Schafer, C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4), G726-G734 (2003) :|Raimondi, L., et al. J. Cell. Mol. Med. 7(1):35-42(2003)|Nastasi, T., et al. Neuroreport 11(10):2233-2236(2000)
USBio References
No references available
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