Technical Data

040135
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E FC WB
Crossreactivity
Hu
Gene ID
23236
Gene #
PLCB1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PLCB1, CT (PLCB1, KIAA0581, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, Phospholipase C-beta-1)
PLCB1, KIAA0581, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, PLC-154, Phosphoinositide phospholipase C-beta-1, Phospholipase C-I, Phospholipase C-beta-1

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PLCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1155~1184 amino acids from the C-terminal region of human PLCB1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Recognizes human PLCB1

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)|Woodcock, E.A., et al. J. Mol. Cell. Cardiol. 47(5):676-683(2009)|Zhang, Y., et al. J. Recept. Signal Transduct. Res. 29(1):52-62(2009)
USBio References
No references available
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