Technical Data

040161
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001036128.1; O94827; NP_001036129.1
Gene ID
57449
Gene #
PLEKHG5
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PLEKHG5, NT (PLEKHG5, KIAA0720, Pleckstrin homology domain-containing family G member 5, Guanine nucleotide exchange factor 720)
PLEKHG5, KIAA0720, Pleckstrin homology domain-containing family G member 5, Guanine nucleotide exchange factor 720

This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Multations in this gene have been found in a family with distal spinal muscular atrophy.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PLEKHG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-202 amino acids from the N-terminal region of human PLEKHG5.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)|Newton-Cheh, C., et al. Nat. Genet. 41(4):399-406(2009)|Maystadt, I., et al. Am. J. Hum. Genet. 81(1):67-76(2007)|Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :|Matsuda, A., et al. Oncogene 22(21):3307-3318(2003)
USBio References
No references available
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