Technical Data

040186
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
NP_065086.2; NP_001121778.1; NP_001170775.1
Gene ID
57088
Gene #
PLSCR4
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PLSCR4, ID (PLSCR4, Phospholipid scramblase 4, Ca(2+)-dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, TRA1)
PLSCR4, Phospholipid scramblase 4, Ca(2+)-dependent phospholipid scramblase 4, Cell growth-inhibiting gene 43 protein, TRA1

PLSCR4 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PLSCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-151 amino acids from the Central region of human PLSCR4.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse (predicted)

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Sahu, S.K., et al. Biochim. Biophys. Acta 1790(10):1274-1281(2009)|Py, B., et al. PLoS ONE 4 (3), E5006 (2009) :|Shibata, H., et al. J. Biol. Chem. 283(15):9623-9632(2008)|Wiedmer, T., et al. Biochim. Biophys. Acta 1467(1):244-253(2000)
USBio References
No references available
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