Technical Data

040626
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_065173.2
Gene ID
5738
Gene #
PTGFRN
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PTGFRN, ID (PTGFRN, CD9P1, EWIF, FPRP, KIAA1436, Prostaglandin F2 receptor negative regulator, CD9 partner 1, Glu-Trp-Ile EWI motif-containing protein F, Prostaglandin F2-alpha receptor regulatory protein, Prostaglandin F2-alpha receptor-associated protein, CD315)
PTGFRN, CD9P1, EWIF, FPRP, KIAA1436, Prostaglandin F2 receptor negative regulator, CD9 partner 1, Glu-Trp-Ile EWI motif-containing protein F, Prostaglandin F2-alpha receptor regulatory protein, Prostaglandin F2-alpha receptor-associated protein, CD315

PTGFRN inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity).

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilutions
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 458-485 in the central region of human PTGFRN.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Recognizes human PTGFRN. Species Crossreactivity: mouse.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Ikeda, M., et al. Biol. Psychiatry 67(3):263-269(2010). 2. Andre, M., et al. J Proteomics 73(1):93-102(2009). 3. Andre, M., et al. Proteomics 7(21):3880-3895(2007). 4. Abache, T., et al. J. Cell. Biochem. 102(3):650-664(2007). 5. Sala-Valdes, M., et al. J. Biol. Chem. 281(28):19665-19675(2006)
USBio References
No references available
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