Technical Data

040627
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_000951.1
Gene ID
5739
Gene #
PTGIR
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-PTGIR, ID (PTGIR, PRIPR, Prostacyclin receptor, Prostaglandin I2 receptor, Prostanoid IP receptor)
PTGIR, PRIPR, Prostacyclin receptor, Prostaglandin I2 receptor, Prostanoid IP receptor

The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
PTGIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 amino acids from the Central region of human PTGIR.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Ibrahim, S., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1802-1809(2010)|Reid, H.M., et al. J. Biol. Chem. 285(24):18709-18726(2010)|Muto, A., et al. Int Angiol 29 (2 SUPPL), 43-48 (2010) :|Davila, S., et al. Genes Immun. 11(3):232-238(2010)
USBio References
No references available
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