040838
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
Hu MoAccession #
NP_057236.1; NP_000956.2Gene ID
5915Gene #
RARBShipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-RARB, NT (RARB, HAP, NR1B2, Retinoic acid receptor beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon)
RARB, HAP, NR1B2, Retinoic acid receptor beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined. [provided by RefSeq].
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
RARB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human RARB.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Miladi-Abdennadher, I., et al. Tumour Biol. 31(5):503-511(2010)|Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)|Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :|Ding, Y., et al. Mol. Vis. 16, 855-861 (2010) :USBio References
No references available