Technical Data

040894
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_909122.1; NP_004893.1
Gene ID
9584
Gene #
RBM39
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-RBM39, NT (RBM39, HCC1, RNPC2, RNA-binding protein 39, Hepatocellular carcinoma protein 1, RNA-binding motif protein 39, RNA-binding region-containing protein 2, Splicing factor HCC1)
RBM39, HCC1, RNPC2, RNA-binding protein 39, Hepatocellular carcinoma protein 1, RNA-binding motif protein 39, RNA-binding region-containing protein 2, Splicing factor HCC1

The protein encoded by this gene is an RNA binding protein and possible splicing factor. The encoded protein is found in the nucleus, where it colocalizes with core spliceosomal proteins. Studies of a mouse protein with high sequence similarity to this protein suggest that this protein may act as a transcriptional coactivator for JUN/AP-1 and estrogen receptors. Multiple transcript variants encoding different isoforms have been observed for this gene.

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 114-143 in the N-terminal region of human RBM39. Species sequence homology: mouse
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human RBM39.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Mercier, I., et al. Am. J. Pathol. 174(4):1172-1190(2009) 2. Dutta, J., et al. J. Virol. 82(21):10792-10802(2008) 3. Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007) 4. Olsen, J.V., et al. Cell 127(3):635-648(2006)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net