040907
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_005049.1Gene ID
5940Gene #
RBMY1A1Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-RBMY1A1, CT (RNA-binding motif protein, Y chromosome, family 1 member A1/C,RBM1, RBM2, YRRM1)
RNA-binding motif protein, Y chromosome, family 1 member A1/C,RBM1, RBM2, YRRM1
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq].
Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 468-496 in the C-terminal region of human RBMY1A1
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human RBMY1A1
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Dreumont, N., et al. J. Cell. Sci. 123 (PT 1), 40-50 (2010). 2. Liu, Y., et al. PLoS Genet. 5 (11), E1000707 (2009). 3. Lardone, M.C., et al. Mol. Hum. Reprod. 13(10):705-712(2007). 4. Skrisovska, L., et al. EMBO Rep. 8(4):372-379(2007). 5. Lavery, R., et al. Arch. Androl. 53(2):71-73(2007).USBio References
No references available