RBP4, NT (RBP4, Retinol-binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176))

040911

Clone Type

Polyclonal

Host

Rabbit

Source

Mouse

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NP_006735.2

Gene ID

5950

Gene #

RBP4

Shipping Temp

Blue Ice

Storage Temp

-20°C

Rabbit Anti-RBP4, NT (RBP4, Retinol-binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176))

RBP4, Retinol-binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176)

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.

Applications

Suitable for use in Western Blot, ELISA

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

RBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human RBP4.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References

Wang, S.N., et al. J. Formos. Med. Assoc. 109(6):422-429(2010)|Liu, X.H., et al. Zhonghua Yi Xue Za Zhi 90(18):1251-1254(2010)|Ku, Y.H., et al. J. Int. Med. Res. 38(3):782-791(2010)|Giacomozzi, C., et al. J. Endocrinol. Invest. 33(4):218-221(2010)|Nair, A.K., et al. PLoS ONE 5 (7), E11444 (2010) :

USBio References

No references available

Technical Data

040911

Clone Type

Host

Source

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

Rabbit Anti-RBP4, NT (RBP4, Retinol-binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176))

RBP4, Retinol-binding protein 4, Plasma retinol-binding protein, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176)

References

USBio References