Rabbit Anti-RC3H1, CT (RC3H1, KIAA2025, RNF198, Roquin, RING finger and C3H zinc finger protein 1, RING finger protein 198)
RC3H1, KIAA2025, RNF198, Roquin, RING finger and C3H zinc finger protein 1, RING finger protein 198
RC3H1, or roquin, encodes a highly conserved member of the RING type ubiquitin ligase protein family (Vinuesa et al., 2005 [PubMed 15917799]). The roquin protein is distinguished by the presence of a CCCH zinc finger found in RNA-binding proteins, and localization to cytosolic RNA granules implicated in regulating mRNA translation and stability.
Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
RC3H1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1014-1043 amino acids from the C-terminal region of human RC3H1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
